Synthesis and Spectral Studies of (2-(furanyl)vinyl)-1-tetralone Chalcones
Take a look at our latest publication in Heterocyclic Letters featuring 5 undergraduate coauthors: Andrew Goetz, Jessica Futch, Kathryn Brown, Maya Wallace, and Morgan Moore.
Ten chalcones were synthesized by the crossed aldol condensation of substituted tetralones with furaldehydes. The products were purified by recrystallization in MeOH/H2O or by column chromatography in hexane/ethyl acetate and characterized by 1H NMR, 13C NMR, and HRMS. Evaluations of their biological activities are currently underway.